Unravelling the story of protein misfolding in diabetes mellitus

Por Thomas, Sally E, Dalton, Lucy, Malzer, Elke, Marciniak, Stefan J
Publicado em 2011

MesobanK UK: an international mesothelioma bioresource

Por Rintoul, Robert C, Rassl, Doris M, Gittins, Jacki, Marciniak, Stefan J
Publicado no Thorax (2016)

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK

Por Marciniak, Stefan J., Garcia-Bonilla, Lidia, Hu, Junjie, Harding, Heather P., Ron, David
Publicado em 2006

Endoplasmic reticulum polymers impair luminal protein mobility and sensitise to cellular stress in α(1)-antitrypsin deficiency

Por Ordóñez, Adriana, Snapp, Erik L, Tan, Lu, Miranda, Elena, Marciniak, Stefan J, Lomas, David A
Publicado em 2013

Neuroserpin Polymers Activate NF-κB by a Calcium Signaling Pathway That Is Independent of the Unfolded Protein Response

Por Davies, Mark J., Miranda, Elena, Roussel, Benoit D., Kaufman, Randal J., Marciniak, Stefan J., Lomas, David A.
Publicado em 2009

Endoplasmic Reticulum-associated Degradation (ERAD) and Autophagy Cooperate to Degrade Polymerogenic Mutant Serpins

Por Kroeger, Heike, Miranda, Elena, MacLeod, Ian, Pérez, Juan, Crowther, Damian C., Marciniak, Stefan J., Lomas, David A.
Publicado em 2009

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

Por Marciniak, Stefan J., Yun, Chi Y., Oyadomari, Seiichi, Novoa, Isabel, Zhang, Yuhong, Jungreis, Rivka, Nagata, Kazuhiro, Harding, Heather P., Ron, David
Publicado em 2004

Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system

Por Ulbrich, Lisa, Favaloro, Flores Lietta, Trobiani, Laura, Marchetti, Valentina, Patel, Vruti, Pascucci, Tiziana, Comoletti, Davide, Marciniak, Stefan J., De Jaco, Antonella
Publicado no Biochem J (2016)

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

Por Lu, Phoebe D, Jousse, Céline, Marciniak, Stefan J, Zhang, Yuhong, Novoa, Isabel, Scheuner, Donalyn, Kaufman, Randal J, Ron, David, Harding, Heather P
Publicado em 2004

Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation

Por Chambers, Joseph E, Dalton, Lucy E, Clarke, Hanna J, Malzer, Elke, Dominicus, Caia S, Patel, Vruti, Moorhead, Greg, Ron, David, Marciniak, Stefan J
Publicado no eLife (2015)

The TRiC/CCT Chaperone Is Implicated in Alzheimer's Disease Based on Patient GWAS and an RNAi Screen in Aβ-Expressing Caenorhabditis elegans

Por Khabirova, Eleonora, Moloney, Aileen, Marciniak, Stefan J., Williams, Julie, Lomas, David A., Oliver, Stephen G., Favrin, Giorgio, Sattelle, David B., Crowther, Damian C.
Publicado em 2014

G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases

Por Chen, Ruming, Rato, Cláudia, Yan, Yahui, Crespillo-Casado, Ana, Clarke, Hanna J, Harding, Heather P, Marciniak, Stefan J, Read, Randy J, Ron, David
Publicado no eLife (2015)

Coordinate regulation of eIF2α phosphorylation by PPP1R15 and GCN2 is required during Drosophila development

Por Malzer, Elke, Szajewska-Skuta, Małgorzata, Dalton, Lucy E., Thomas, Sally E., Hu, Nan, Skaer, Helen, Lomas, David A., Crowther, Damian C., Marciniak, Stefan J.
Publicado em 2013

Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells

Por van ‘t Wout, Emily F. A., van Schadewijk, Annemarie, van Boxtel, Ria, Dalton, Lucy E., Clarke, Hanna J., Tommassen, Jan, Marciniak, Stefan J., Hiemstra, Pieter S.
Publicado no PLoS Pathog (2015)

Iron Promotes the Toxicity of Amyloid β Peptide by Impeding Its Ordered Aggregation

Por Liu, Beinan, Moloney, Aileen, Meehan, Sarah, Morris, Kyle, Thomas, Sally E., Serpell, Louise C., Hider, Robert, Marciniak, Stefan J., Lomas, David A., Crowther, Damian C.
Publicado em 2011

p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress

Por Thomas, Sally E., Malzer, Elke, Ordóñez, Adriana, Dalton, Lucy E., van ′t Wout, Emily F. A., Liniker, Elizabeth, Crowther, Damian C., Lomas, David A., Marciniak, Stefan J.
Publicado em 2013

Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response

Por Malzer, Elke, Daly, Marie-Louise, Moloney, Aileen, Sendall, Timothy J., Thomas, Sally E., Ryder, Edward, Ryoo, Hyung Don, Crowther, Damian C., Lomas, David A., Marciniak, Stefan J.
Publicado em 2010

A single-chain variable fragment intrabody prevents intracellular polymerization of Z α(1)-antitrypsin while allowing its antiproteinase activity

Por Ordóñez, Adriana, Pérez, Juan, Tan, Lu, Dickens, Jennifer A., Motamedi-Shad, Neda, Irving, James A., Haq, Imran, Ekeowa, Ugo, Marciniak, Stefan J., Miranda, Elena, Lomas, David A.
Publicado no FASEB J (2015)

Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity()

Por Kruppa, Antonina J., Ott, Stanislav, Chandraratna, Dhia S., Irving, James A., Page, Richard M., Speretta, Elena, Seto, Tiffany, Camargo, Luiz Miguel, Marciniak, Stefan J., Lomas, David A., Crowther, Damian C.
Publicado em 2013

Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB

Por Roussel, Benoit D., Newton, Timothy M., Malzer, Elke, Simecek, Nikol, Haq, Imran, Thomas, Sally E., Burr, Marian L., Lehner, Paul J., Crowther, Damian C., Marciniak, Stefan J., Lomas, David A.
Publicado em 2013