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Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2
Transient phosphorylation of the α-subunit of translation initiation factor 2 (eIF2α) represses translation and activates select gene expression under diverse stressful conditions. Defects in the eIF2α phosphorylation-dependent integrated stress response impair resistance to accumulation of malfolde...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271668/ https://ncbi.nlm.nih.gov/pubmed/14713949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600030 |
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