Llwytho...

Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression

Phosphorylation of translation initiation factor 2α (eIF2α ) coordinates a translational and transcriptional program known as the integrated stress response (ISR), which adapts cells to endoplasmic reticulum (ER) stress. A screen for small molecule activators of the ISR identified two related compou...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Harding, Heather P., Zhang, Yuhong, Khersonsky, Sonya, Marciniak, Stefan, Scheuner, Donalyn, Kaufman, Randal J., Javitt, Norman, Chang, Young-Tae, Ron, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1361344/
https://ncbi.nlm.nih.gov/pubmed/16330322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2005.11.005
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