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The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes

The endoplasmic reticulum (ER) is the entry site into the secretory pathway for newly synthesized proteins destined for the cell surface or released into the extracellular milieu. The study of protein folding and trafficking within the ER is an extremely active area of research that has provided nov...

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Detalhes bibliográficos
Main Authors: Scheuner, Donalyn, Kaufman, Randal J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528859/
https://ncbi.nlm.nih.gov/pubmed/18436705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2007-0039
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