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Phosphorylation of Eukaryotic Translation Initiation Factor 2α Coordinates rRNA Transcription and Translation Inhibition during Endoplasmic Reticulum Stress

The endoplasmic reticulum (ER) is the major cellular compartment where folding and maturation of secretory and membrane proteins take place. When protein folding needs exceed the capacity of the ER, the unfolded protein response (UPR) pathway modulates gene expression and downregulates protein trans...

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Bibliografski detalji
Glavni autori: DuRose, Jenny B., Scheuner, Donalyn, Kaufman, Randal J., Rothblum, Lawrence I., Niwa, Maho
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715810/
https://ncbi.nlm.nih.gov/pubmed/19470760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00260-09
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