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The Endoplasmic Reticulum and the Unfolded Protein Response
The endoplasmic reticulum (ER) is the site where proteins enter the secretory pathway. Proteins are translocated into the ER lumen in an unfolded state and require protein chaperones and catalysts of protein folding to attain their final appropriate conformation. A sensitive surveillance mechanism e...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706143/ https://ncbi.nlm.nih.gov/pubmed/18023214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2007.09.003 |
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