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The Cellular Response to Protein Misfolding in the Endoplasmic Reticulum
In eukaryotic cells, accumulation of unfolded proteins in the lumen of the endoplasmic reticulum (ER) leads to a stress response. Cells respond to ER stress by upregulating the synthesis of ER resident protein chaperones, thus increasing the folding capacity in this organelle. In addition, this resp...
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| Veröffentlicht in: | Gene Expr |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cognizant Communication Corporation
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6174664/ https://ncbi.nlm.nih.gov/pubmed/10440230 |
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