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Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

Protein misfolding in the endoplasmic reticulum (ER) contributes to the pathogenesis of many diseases. Although oxidative stress can disrupt protein folding, how protein misfolding and oxidative stress impact each other has not been explored. We have analyzed expression of coagulation factor VIII (F...

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Bibliografski detalji
Glavni autori: Malhotra, Jyoti D., Miao, Hongzhi, Zhang, Kezhong, Wolfson, Anna, Pennathur, Subramaniam, Pipe, Steven W., Kaufman, Randal J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587584/
https://ncbi.nlm.nih.gov/pubmed/19011102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809677105
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