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Endoplasmic Reticulum Stress in Liver Disease
The unfolded protein response (UPR) is activated upon the accumulation of misfolded proteins in the endoplasmic reticulum (ER), that are sensed by the binding immunoglobulin protein (BiP)/glucose-regulated protein 78 (GRP78). The accumulation of unfolded proteins sequesters BiP so it dissociates fro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375108/ https://ncbi.nlm.nih.gov/pubmed/21145844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2010.11.005 |
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