Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3

Por Petrova, Kseniya, Oyadomari, Seiichi, Hendershot, Linda M, Ron, David
Publicado em 2008

Integrated stress response of vertebrates is regulated by four eIF2α kinases

Por Taniuchi, Shusuke, Miyake, Masato, Tsugawa, Kazue, Oyadomari, Miho, Oyadomari, Seiichi
Publicado no Sci Rep (2016)

De-phosphorylation of translation initiation factor 2α (eIF2α) enhances glucose tolerance and attenuates hepato-steatosis in mice

Por Oyadomari, Seiichi, Harding, Heather P., Zhang, Yuhong, Oyadomari, Miho, Ron, David
Publicado em 2008

Induction of molecular chaperones in carbon tetrachloride–treated rat liver: implications in protection against liver damage

Por Lee, Kwang-Jong, Terada, Kazutoyo, Oyadomari, Seiichi, Inomata, Yukihiro, Mori, Masataka, Gotoh, Tomomi
Publicado em 2004

Targeted disruption of the Chop gene delays endoplasmic reticulum stress–mediated diabetes

Por Oyadomari, Seiichi, Koizumi, Akio, Takeda, Kiyoshi, Gotoh, Tomomi, Akira, Shizuo, Araki, Eiichi, Mori, Masataka
Publicado em 2002

Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress

Por Yamamoto, Keisuke, Takahara, Kazuna, Oyadomari, Seiichi, Okada, Tetsuya, Sato, Takashi, Harada, Akihiro, Mori, Kazutoshi
Publicado em 2010

Inhibition of a constitutive translation initiation factor 2α phosphatase, CReP, promotes survival of stressed cells

Por Jousse, Céline, Oyadomari, Seiichi, Novoa, Isabel, Lu, Phoebe, Zhang, Yuhong, Harding, Heather P., Ron, David
Publicado em 2003

Nitric oxide-induced apoptosis in pancreatic β cells is mediated by the endoplasmic reticulum stress pathway

Por Oyadomari, Seiichi, Takeda, Kiyoshi, Takiguchi, Masaki, Gotoh, Tomomi, Matsumoto, Makoto, Wada, Ikuo, Akira, Shizuo, Araki, Eiichi, Mori, Masataka
Publicado em 2001

PERK-mediated translational control is required for collagen secretion in chondrocytes

Por Hisanaga, Satoshi, Miyake, Masato, Taniuchi, Shusuke, Oyadomari, Miho, Morimoto, Masatoshi, Sato, Ryosuke, Hirose, Jun, Mizuta, Hiroshi, Oyadomari, Seiichi
Publicado no Sci Rep (2018)

Nanosecond pulsed electric fields induce the integrated stress response via reactive oxygen species-mediated heme-regulated inhibitor (HRI) activation

Por Hamada, Yoshimasa, Furumoto, Yuji, Izutani, Akira, Taniuchi, Shusuke, Miyake, Masato, Oyadomari, Miho, Teranishi, Kenji, Shimomura, Naoyuki, Oyadomari, Seiichi
Publicado no PLoS One (2020)

Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems

Por Yasue, Akihiro, Mitsui, Silvia Naomi, Watanabe, Takahito, Sakuma, Tetsushi, Oyadomari, Seiichi, Yamamoto, Takashi, Noji, Sumihare, Mito, Taro, Tanaka, Eiji
Publicado em 2014

Novel human mutation and CRISPR/Cas genome-edited mice reveal the importance of C-terminal domain of MSX1 in tooth and palate development

Por Mitsui, Silvia Naomi, Yasue, Akihiro, Masuda, Kiyoshi, Naruto, Takuya, Minegishi, Yoshiyuki, Oyadomari, Seiichi, Noji, Sumihare, Imoto, Issei, Tanaka, Eiji
Publicado no Sci Rep (2016)

Relationship between somatic mosaicism of Pax6 mutation and variable developmental eye abnormalities—an analysis of CRISPR genome-edited mouse embryos

Por Yasue, Akihiro, Kono, Hitomi, Habuta, Munenori, Bando, Tetsuya, Sato, Keita, Inoue, Junji, Oyadomari, Seiichi, Noji, Sumihare, Tanaka, Eiji, Ohuchi, Hideyo
Publicado no Sci Rep (2017)

Ligand-induced rapid skeletal muscle atrophy in HSA-Fv2E-PERK transgenic mice

Por Miyake, Masato, Kuroda, Masashi, Kiyonari, Hiroshi, Takehana, Kenji, Hisanaga, Satoshi, Morimoto, Masatoshi, Zhang, Jun, Oyadomari, Miho, Sakaue, Hiroshi, Oyadomari, Seiichi
Publicado no PLoS One (2017)

A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition

Por Kitajima, Shojiro, Sun, Wendi, Lee, Kian Leong, Ho, Jolene Caifeng, Oyadomari, Seiichi, Okamoto, Takashi, Masai, Hisao, Poellinger, Lorenz, Kato, Hiroyuki
Publicado no Sci Rep (2021)

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

Por Marciniak, Stefan J., Yun, Chi Y., Oyadomari, Seiichi, Novoa, Isabel, Zhang, Yuhong, Jungreis, Rivka, Nagata, Kazuhiro, Harding, Heather P., Ron, David
Publicado em 2004

Concomitant Nrf2- and ATF4-Activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes

Por Mimura, Junsei, Inose-Maruyama, Atsushi, Taniuchi, Shusuke, Kosaka, Kunio, Yoshida, Hidemi, Yamazaki, Hiromi, Kasai, Shuya, Harada, Nobuhiko, Kaufman, Randal J., Oyadomari, Seiichi, Itoh, Ken
Publicado no Int J Mol Sci (2019)

Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity

Por Kitakaze, Keisuke, Taniuchi, Shusuke, Kawano, Eri, Hamada, Yoshimasa, Miyake, Masato, Oyadomari, Miho, Kojima, Hirotatsu, Kosako, Hidetaka, Kuribara, Tomoko, Yoshida, Suguru, Hosoya, Takamitsu, Oyadomari, Seiichi
Publicado no eLife (2019)

Activation of PERK-ATF4-CHOP pathway as a novel therapeutic approach for efficient elimination of HTLV-1–infected cells

Por Ikebe, Emi, Matsuoka, Sahoko, Tezuka, Kenta, Kuramitsu, Madoka, Okuma, Kazu, Nakashima, Makoto, Kobayashi, Seiichiro, Makiyama, Junya, Yamagishi, Makoto, Oyadomari, Seiichi, Uchimaru, Kaoru, Hamaguchi, Isao
Publicado no Blood Adv (2020)

Fgf10-CRISPR mosaic mutants demonstrate the gene dose-related loss of the accessory lobe and decrease in the number of alveolar type 2 epithelial cells in mouse lung

Por Habuta, Munenori, Yasue, Akihiro, Suzuki, Ken-ichi T., Fujita, Hirofumi, Sato, Keita, Kono, Hitomi, Takayama, Ayuko, Bando, Tetsuya, Miyaishi, Satoru, Oyadomari, Seiichi, Tanaka, Eiji, Ohuchi, Hideyo
Publicado no PLoS One (2020)