Relationship between somatic mosaicism of Pax6 mutation and variable developmental eye abnormalities—an analysis of CRISPR genome-edited mouse embryos

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) system is a rapid gene-targeting technology that does not require embryonic stem cells. To demonstrate dosage effects of the Pax6 gene on eye formation, we generated Pax6-deficient mice with the CRI...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yasue, Akihiro, Kono, Hitomi, Habuta, Munenori, Bando, Tetsuya, Sato, Keita, Inoue, Junji, Oyadomari, Seiichi, Noji, Sumihare, Tanaka, Eiji, Ohuchi, Hideyo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428340/
https://ncbi.nlm.nih.gov/pubmed/28246397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00088-w
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados