Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress

Accumulation of unfolded proteins in the endoplasmic reticulum (ER) activates homeostatic responses collectively termed the unfolded protein response. Among the three principal signaling pathways operating in mammals, activating transcription factor (ATF)6α plays a pivotal role in transcriptional in...

Full description

Saved in:
Bibliographic Details
Main Authors: Yamamoto, Keisuke, Takahara, Kazuna, Oyadomari, Seiichi, Okada, Tetsuya, Sato, Takashi, Harada, Akihiro, Mori, Kazutoshi
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2010
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929991/
https://ncbi.nlm.nih.gov/pubmed/20631254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-02-0133
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items