The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity

While ATF6α plays a central role in the endoplasmic reticulum (ER) stress response, the function of its paralogue ATF6β remains elusive, especially in the central nervous system (CNS). Here, we demonstrate that ATF6β is highly expressed in the hippocampus of the brain, and specifically regulates the...

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Publicado no:Sci Rep
Main Authors: Nguyen, Dinh Thi, Le, Thuong Manh, Hattori, Tsuyoshi, Takarada-Iemata, Mika, Ishii, Hiroshi, Roboon, Jureepon, Tamatani, Takashi, Kannon, Takayuki, Hosomichi, Kazuyoshi, Tajima, Atsushi, Taniuchi, Shusuke, Miyake, Masato, Oyadomari, Seiichi, Tanaka, Takashi, Kato, Nobuo, Saito, Shunsuke, Mori, Kazutoshi, Hori, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219835/
https://ncbi.nlm.nih.gov/pubmed/34158584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92529-w
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