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Role of Disulfide Bridges Formed in the Luminal Domain of ATF6 in Sensing Endoplasmic Reticulum Stress

ATF6 is a membrane-bound transcription factor activated by proteolysis in response to endoplasmic reticulum (ER) stress to induce the transcription of ER chaperone genes. We show here that, owing to the presence of intra- and intermolecular disulfide bridges formed between the two conserved cysteine...

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書誌詳細
主要な著者: Nadanaka, Satomi, Okada, Tetsuya, Yoshida, Hiderou, Mori, Kazutoshi
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800683/
https://ncbi.nlm.nih.gov/pubmed/17101776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00408-06
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