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Role of Disulfide Bridges Formed in the Luminal Domain of ATF6 in Sensing Endoplasmic Reticulum Stress

ATF6 is a membrane-bound transcription factor activated by proteolysis in response to endoplasmic reticulum (ER) stress to induce the transcription of ER chaperone genes. We show here that, owing to the presence of intra- and intermolecular disulfide bridges formed between the two conserved cysteine...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nadanaka, Satomi, Okada, Tetsuya, Yoshida, Hiderou, Mori, Kazutoshi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800683/
https://ncbi.nlm.nih.gov/pubmed/17101776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00408-06
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