Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress

Accumulation of unfolded proteins in the endoplasmic reticulum (ER) activates homeostatic responses collectively termed the unfolded protein response. Among the three principal signaling pathways operating in mammals, activating transcription factor (ATF)6α plays a pivotal role in transcriptional in...

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Autores principales: Yamamoto, Keisuke, Takahara, Kazuna, Oyadomari, Seiichi, Okada, Tetsuya, Sato, Takashi, Harada, Akihiro, Mori, Kazutoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2010
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929991/
https://ncbi.nlm.nih.gov/pubmed/20631254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-02-0133
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