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PERK-mediated translational control is required for collagen secretion in chondrocytes

As chondrocytes are highly secretory and they experience a variety of stresses, physiological unfolded protein response (UPR) signalling is essential for extracellular matrix (ECM) secretion and chondrogenesis. In the three branches of the UPR pathway, PERK governs the translational attenuation and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hisanaga, Satoshi, Miyake, Masato, Taniuchi, Shusuke, Oyadomari, Miho, Morimoto, Masatoshi, Sato, Ryosuke, Hirose, Jun, Mizuta, Hiroshi, Oyadomari, Seiichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768675/
https://ncbi.nlm.nih.gov/pubmed/29335505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-19052-9
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