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PERK-mediated translational control is required for collagen secretion in chondrocytes

As chondrocytes are highly secretory and they experience a variety of stresses, physiological unfolded protein response (UPR) signalling is essential for extracellular matrix (ECM) secretion and chondrogenesis. In the three branches of the UPR pathway, PERK governs the translational attenuation and...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Hisanaga, Satoshi, Miyake, Masato, Taniuchi, Shusuke, Oyadomari, Miho, Morimoto, Masatoshi, Sato, Ryosuke, Hirose, Jun, Mizuta, Hiroshi, Oyadomari, Seiichi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768675/
https://ncbi.nlm.nih.gov/pubmed/29335505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-19052-9
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