Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase η for A/T

Por Neuberger, Michael S., Rada, Cristina
Publicado em 2007

B cells extract and present immobilized antigen: implications for affinity discrimination

Por Batista, Facundo D., Neuberger, Michael S.
Publicado em 2000

The Immunoglobulin (Ig)α and Igβ Cytoplasmic Domains Are Independently Sufficient to Signal B Cell Maturation and Activation in Transgenic Mice

Por Teh, Yih-Miin, Neuberger, Michael S.
Publicado em 1997

Human APOBEC3G Can Restrict Retroviral Infection in Avian Cells and Acts Independently of both UNG and SMUG1

Por Langlois, Marc-André, Neuberger, Michael S.
Publicado em 2008

Both DNA strands of antibody genes are hypermutation targets

Por Milstein, Cesar, Neuberger, Michael S., Staden, Rodger
Publicado em 1998

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2 (−/−) ung (−/−) mice

Por Xue, Kanmin, Rada, Cristina, Neuberger, Michael S.
Publicado em 2006

The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence

Por Geisberger, Roland, Rada, Cristina, Neuberger, Michael S.
Publicado em 2009

Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID

Por Wang, Meng, Rada, Cristina, Neuberger, Michael S.
Publicado em 2010

Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A)

Por Häsler, Julien, Rada, Cristina, Neuberger, Michael S.
Publicado em 2011

Preface

Por Gearhart, Patricia J., Lindahl, Tomas, Neuberger, Michael S.
Publicado em 2008

SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair

Por Di Noia, Javier M, Rada, Cristina, Neuberger, Michael S
Publicado em 2006

Deficiency in Serum Immunoglobulin (Ig)m Predisposes to Development of Igg Autoantibodies

Por Ehrenstein, Michael R., Cook, H. Terence, Neuberger, Michael S.
Publicado em 2000

AID up-mutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity

Por Wang, Meng, Yang, Zizhen, Rada, Cristina, Neuberger, Michael S.
Publicado no Nat Struct Mol Biol (2009)

The AKV Murine Leukemia Virus Is Restricted and Hypermutated by Mouse APOBEC3

Por Langlois, Marc-André, Kemmerich, Kristin, Rada, Cristina, Neuberger, Michael S.
Publicado em 2009

REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase

Por Uchimura, Yasuhiro, Barton, Lance F., Rada, Cristina, Neuberger, Michael S.
Publicado em 2011

Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung(−/−)Msh2(−/−)...

Por Kemmerich, Kristin, Dingler, Felix A., Rada, Cristina, Neuberger, Michael S.
Publicado em 2012

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation

Por Dingler, Felix A., Kemmerich, Kristin, Neuberger, Michael S., Rada, Cristina
Publicado em 2014

Epstein-Barr Virus and the Somatic Hypermutation of Immunoglobulin Genes in Burkitt's Lymphoma Cells

Por Harris, Reuben S., Croom-Carter, Debbie S. G., Rickinson, Alan B., Neuberger, Michael S.
Publicado em 2001

Deficiency in CD22, a B Cell–specific Inhibitory Receptor, Is Sufficient to Predispose to Development of High Affinity Autoantibodies

Por O'Keefe, Theresa L., Williams, Gareth T., Batista, Facundo D., Neuberger, Michael S.
Publicado em 1999

The dependence of Ig class-switching on the nuclear export sequence of AID likely reflects interaction with factors additional to Crm1 exportin

Por Ellyard, Julia I, Benk, Amelie S, Taylor, Benjamin, Rada, Cristina, Neuberger, Michael S
Publicado em 2011