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The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence
The carboxyterminal region of activation-induced deaminase (AID) is required for its function in Ig class switch recombination (CSR) and also contains a nuclear-export sequence (NES). Here, based on an extensive fine-structure mutation analysis of the AID NES, as well as from AID chimeras bearing he...
সংরক্ষণ করুন:
প্রধান লেখক: | , , |
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বিন্যাস: | Artigo |
ভাষা: | Inglês |
প্রকাশিত: |
National Academy of Sciences
2009
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বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672500/ https://ncbi.nlm.nih.gov/pubmed/19351893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810808106 |
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