Chargement en cours...
Lysine Residue at Position 22 of the AID Protein Regulates Its Class Switch Activity
BACKGROUND: Activation induced deaminase (AID) mediates class switch recombination and somatic hypermutation of immunoglobulin (Ig) genes in germinal centre B cells. In order to regulate its specific activity and as a means to keep off-target mutations low, several mechanisms have evolved, including...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282692/ https://ncbi.nlm.nih.gov/pubmed/22363466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030667 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|