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Chronic lymphocytic leukaemia induces an exhausted T cell phenotype in the TCL1 transgenic mouse model

Although chronic lymphocytic leukaemia (CLL) is a B cell malignancy, earlier studies have indicated a role of T cells in tumour growth and disease progression. In particular, the functional silencing of antigen-experienced T cells, called T cell exhaustion, has become implicated in immune evasion in...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Gassner, Franz J, Zaborsky, Nadja, Catakovic, Kemal, Rebhandl, Stefan, Huemer, Michael, Egle, Alexander, Hartmann, Tanja N, Greil, Richard, Geisberger, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687418/
https://ncbi.nlm.nih.gov/pubmed/25940792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13467
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