TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia

While research on T cell exhaustion in context of cancer particularly focuses on CD8+ cytotoxic T cells, the role of inhibitory receptors on CD4+ T-helper cells have remained largely unexplored. TIGIT is a recently identified inhibitory receptor on T cells and natural killer (NK) cells. In this stud...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Catakovic, Kemal, Gassner, Franz Josef, Ratswohl, Christoph, Zaborsky, Nadja, Rebhandl, Stefan, Schubert, Maria, Steiner, Markus, Gutjahr, Julia Christine, Pleyer, Lisa, Egle, Alexander, Hartmann, Tanja Nicole, Greil, Richard, Geisberger, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739567/
https://ncbi.nlm.nih.gov/pubmed/29296521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1371399
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