Evidence for Non-Cancer-Specific T Cell Exhaustion in the Tcl1 Mouse Model for Chronic Lymphocytic Leukemia

The reinvigoration of anti-cancer immunity by immune checkpoint therapies has greatly improved cancer treatment. In chronic lymphocytic leukemia (CLL), patients as well as in the Tcl1 mouse model for CLL, PD1-expressing, exhausted T cells significantly expand alongside CLL development; nevertheless,...

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Pubblicato in:Int J Mol Sci
Autori principali: Parigger, Thomas, Gassner, Franz Josef, Scherhäufl, Christian, Bakar, Aryunni Abu, Höpner, Jan Philip, Hödlmoser, Alexandra, Steiner, Markus, Catakovic, Kemal, Geisberger, Roland, Greil, Richard, Zaborsky, Nadja
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268419/
https://ncbi.nlm.nih.gov/pubmed/34206229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136648
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