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B cells extract and present immobilized antigen: implications for affinity discrimination

Binding of antigen to B–cell antigen receptor (BCR) leads to antigen internalization and presentation to T cells, a critical process in the initiation of the humoral immune response. However, antigen internalization has been demonstrated for soluble antigen, in vivo antigen is often encountered in i...

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Detalhes bibliográficos
Main Authors: Batista, Facundo D., Neuberger, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305589/
https://ncbi.nlm.nih.gov/pubmed/10675320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.4.513
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