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Antigen affinity discrimination is an intrinsic function of the B cell receptor
Antibody affinity maturation, a hallmark of adaptive immune responses, results from the selection of B cells expressing somatically hypermutated B cell receptors (BCRs) with increased affinity for antigens. Despite the central role of affinity maturation in antibody responses, the molecular mechanis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867278/ https://ncbi.nlm.nih.gov/pubmed/20404102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092123 |
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