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Membrane heterogeneities in the formation of B cell receptor–Lyn kinase microclusters and the immune synapse
Antigen binding to the B cell receptors (BCRs) induces BCR clustering, phosphorylation of BCRs by the Src family kinase Lyn, initiation of signaling, and formation of an immune synapse. We investigated B cells as they first encountered antigen on a membrane using live cell high resolution total inte...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483512/ https://ncbi.nlm.nih.gov/pubmed/18644892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200802007 |
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