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Fluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signaling

B cell responses are initiated by the clustering of the B cell receptor (BCR) by the binding of multivalent antigens. Clustering leads to phosphorylation of tyrosines in the cytoplasmic domains of the BCR by the inner plasma membrane leaflet-associated Src-family kinase Lyn. At present, little is kn...

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Autors principals: Sohn, Hae Won, Tolar, Pavel, Jin, Tian, Pierce, Susan K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472443/
https://ncbi.nlm.nih.gov/pubmed/16690746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509858103
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