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B cells use mechanical energy to discriminate antigen affinities
The generation of high-affinity antibodies depends on the ability of B cells to extract antigens from the surfaces of antigen-presenting cells. B cells that express high-affinity B cell receptors (BCRs) acquire more antigen and obtain better T cell help. However, the mechanisms by which B cells extr...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3713314/ https://ncbi.nlm.nih.gov/pubmed/23686338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237572 |
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