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B cell antigen extraction is regulated by physical properties of antigen-presenting cells
Antibody production and affinity maturation are driven by B cell extraction and internalization of antigen from immune synapses. However, the extraction mechanism remains poorly understood. Here we develop DNA-based nanosensors to interrogate two previously proposed mechanisms, enzymatic liberation...
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| Опубликовано в: : | J Cell Biol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223605/ https://ncbi.nlm.nih.gov/pubmed/27923880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607064 |
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