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Germinal center B cells recognize antigen through a specialized immune synapse architecture
B cell activation is regulated by B cell antigen receptor (BCR) signaling and antigen internalization in immune synapses. Using large-scale imaging across B cell subsets, we show that in contrast to naive and memory B cells, which gathered antigen towards the synapse center before internalization, g...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4943528/ https://ncbi.nlm.nih.gov/pubmed/27183103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3458 |
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