Llwytho...

B cell antigen extraction is regulated by physical properties of antigen-presenting cells

Antibody production and affinity maturation are driven by B cell extraction and internalization of antigen from immune synapses. However, the extraction mechanism remains poorly understood. Here we develop DNA-based nanosensors to interrogate two previously proposed mechanisms, enzymatic liberation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Spillane, Katelyn M., Tolar, Pavel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223605/
https://ncbi.nlm.nih.gov/pubmed/27923880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607064
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