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Activation of the B Cell Receptor Leads to Increased Membrane Proximity of the Igα Cytoplasmic Domain
Binding of antigen to the B cell receptor (BCR) induces conformational changes in BCR's cytoplasmic domains that are concomitant with phosphorylation of the immunoreceptor tyrosine-based activation motifs (ITAMs). Recently, reversible folding of the CD3ε and ξ chain ITAMs into the plasma membra...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823606/ https://ncbi.nlm.nih.gov/pubmed/24244439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079148 |
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