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The Immunoglobulin (Ig)α and Igβ Cytoplasmic Domains Are Independently Sufficient to Signal B Cell Maturation and Activation in Transgenic Mice

The B cell antigen receptor, composed of membrane immunoglobulin (Ig) sheathed by the Igα/Igβ heterodimer plays a critical role in mediating B cell development and responses to antigen. The cytoplasmic tails of Igα and Igβ differ substantially but have been well conserved in evolution. Transfection...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Teh, Yih-Miin, Neuberger, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196318/
https://ncbi.nlm.nih.gov/pubmed/9151700
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