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The constant region of the membrane immunoglobulin mediates B-cell receptor clustering and signaling in response to membrane antigens
B cells are activated in vivo following the B-cell receptors (BCRs) binding to antigens captured on the surfaces of antigen presenting cells. Antigen binding results in BCR microclustering and signaling, however, the molecular nature of the signaling-active BCR clusters is not well understood. Using...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656684/ https://ncbi.nlm.nih.gov/pubmed/19135393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.11.007 |
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