Deficiency in Serum Immunoglobulin (Ig)m Predisposes to Development of Igg Autoantibodies

Serum immunoglobulin (Ig)M provides the initial response to foreign antigen and plays a regulatory role in subsequent immune response development, accelerating the production of high-affinity IgG. Here we show that mice deficient in serum IgM have an increased propensity to spontaneous autoimmunity...

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Hlavní autoři: Ehrenstein, Michael R., Cook, H. Terence, Neuberger, Michael S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2000
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193170/
https://ncbi.nlm.nih.gov/pubmed/10748243
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