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SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair
Mammals harbour multiple enzymes capable of excising uracil from DNA, although their distinct physiological roles remain uncertain. One of them (UNG) plays a critical role in antibody gene diversification, as UNG deficiency alone is sufficient to perturb the process. Here, we show this unique requir...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383525/ https://ncbi.nlm.nih.gov/pubmed/16407970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600939 |
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