Excision of uracil from DNA by hSMUG1 includes strand incision and processing

Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. The base excision repair (BER) pathway replaces uracil by the correct base. In...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Alexeeva, Marina, Moen, Marivi N, Grøsvik, Kristin, Tesfahun, Almaz N, Xu, Xiang Ming, Muruzábal-Lecumberri, Izaskun, Olsen, Kristine M, Rasmussen, Anette, Ruoff, Peter, Kirpekar, Finn, Klungland, Arne, Bjelland, Svein
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344882/
https://ncbi.nlm.nih.gov/pubmed/30496516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1184
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