Excision of uracil from DNA by hSMUG1 includes strand incision and processing

Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. The base excision repair (BER) pathway replaces uracil by the correct base. In...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Alexeeva, Marina, Moen, Marivi N, Grøsvik, Kristin, Tesfahun, Almaz N, Xu, Xiang Ming, Muruzábal-Lecumberri, Izaskun, Olsen, Kristine M, Rasmussen, Anette, Ruoff, Peter, Kirpekar, Finn, Klungland, Arne, Bjelland, Svein
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344882/
https://ncbi.nlm.nih.gov/pubmed/30496516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1184
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