Excision of uracil from DNA by hSMUG1 includes strand incision and processing

Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. The base excision repair (BER) pathway replaces uracil by the correct base. In...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Alexeeva, Marina, Moen, Marivi N, Grøsvik, Kristin, Tesfahun, Almaz N, Xu, Xiang Ming, Muruzábal-Lecumberri, Izaskun, Olsen, Kristine M, Rasmussen, Anette, Ruoff, Peter, Kirpekar, Finn, Klungland, Arne, Bjelland, Svein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344882/
https://ncbi.nlm.nih.gov/pubmed/30496516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1184
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi