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Excision of uracil from DNA by hSMUG1 includes strand incision and processing

Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. The base excision repair (BER) pathway replaces uracil by the correct base. In...

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מידע ביבליוגרפי
הוצא לאור ב:	Nucleic Acids Res
Main Authors:	Alexeeva, Marina, Moen, Marivi N, Grøsvik, Kristin, Tesfahun, Almaz N, Xu, Xiang Ming, Muruzábal-Lecumberri, Izaskun, Olsen, Kristine M, Rasmussen, Anette, Ruoff, Peter, Kirpekar, Finn, Klungland, Arne, Bjelland, Svein
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Oxford University Press 2019
נושאים:	Genome Integrity, Repair and Replication
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6344882/ https://ncbi.nlm.nih.gov/pubmed/30496516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1184
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Excision of uracil from DNA by hSMUG1 includes strand incision and processing

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