Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein

DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most thermodynamically unstable base pair, the cytosine (C)⋅C mismatch, destabilizes adja...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Tesfahun, Almaz Nigatu, Alexeeva, Marina, Tomkuvienė, Miglė, Arshad, Aysha, Guragain, Prashanna, Klungland, Arne, Klimašauskas, Saulius, Ruoff, Peter, Bjelland, Svein
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278400/
https://ncbi.nlm.nih.gov/pubmed/34276575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.608839
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