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Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases
Biophysical and mechanistic investigation of RNA function requires site-specific incorporation of spectroscopic and chemical probes, which is difficult to achieve using current technologies. We have in vitro reconstituted a functional box C/D small ribonucleoprotein RNA 2′-O-methyltransferase (C/D R...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413156/ https://ncbi.nlm.nih.gov/pubmed/22564896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks381 |
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