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In vitro RNP assembly and methylation guide activity of an unusual box C/D RNA, cis-acting archaeal pre-tRNA(Trp)

Among the large family of C/D methylation guide RNAs, the intron of euryarchaeal pre-tRNA(Trp) represents an outstanding specimen able to guide in cis, instead of in trans, two 2′-O-methylations in the pre-tRNA exons. Remarkably, both sites of methylation involve nucleotides within the bulge–helix–b...

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Detalhes bibliográficos
Main Authors: Bortolin, Marie-Line, Bachellerie, Jean-Pierre, Clouet-d'Orval, Béatrice
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC275556/
https://ncbi.nlm.nih.gov/pubmed/14602911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg860
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