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Repurposing enzymatic transferase reactions for targeted labeling and analysis of DNA and RNA

Produced as linear biopolymers from four major types of building blocks, DNA and RNA are further furnished with a range of covalent modifications. Despite the impressive specificity of natural enzymes, the transferred groups are often poor reporters and not amenable to further derivatization. Theref...

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Bibliografiske detaljer
Udgivet i:Curr Opin Biotechnol
Main Authors: Tomkuvienė, Miglė, Mickutė, Milda, Vilkaitis, Giedrius, Klimašauskas, Saulius
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513755/
https://ncbi.nlm.nih.gov/pubmed/30296696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2018.09.008
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