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Epstein-Barr Virus and the Somatic Hypermutation of Immunoglobulin Genes in Burkitt's Lymphoma Cells

It has been suggested that Epstein-Barr virus (EBV) might suppress antibody maturation either by facilitating bypass of the germinal center reaction or by inhibiting hypermutation directly. However, by infecting the Burkitt's lymphoma (BL) cell line Ramos, which hypermutates constitutively and...

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Detalhes bibliográficos
Main Authors: Harris, Reuben S., Croom-Carter, Debbie S. G., Rickinson, Alan B., Neuberger, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114624/
https://ncbi.nlm.nih.gov/pubmed/11581418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10488-10492.2001
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