Epstein-Barr Virus and the Somatic Hypermutation of Immunoglobulin Genes in Burkitt's Lymphoma Cells

It has been suggested that Epstein-Barr virus (EBV) might suppress antibody maturation either by facilitating bypass of the germinal center reaction or by inhibiting hypermutation directly. However, by infecting the Burkitt's lymphoma (BL) cell line Ramos, which hypermutates constitutively and...

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Bibliographic Details
Main Authors: Harris, Reuben S., Croom-Carter, Debbie S. G., Rickinson, Alan B., Neuberger, Michael S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114624/
https://ncbi.nlm.nih.gov/pubmed/11581418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10488-10492.2001
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