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Malignant Transformation of Epstein-Barr Virus-Negative Akata Cells by Introduction of the BARF1 Gene Carried by Epstein-Barr Virus

Spontaneous loss of the Epstein-Barr virus (EBV) genome in the BL cell line Akata led to loss of tumorigenicity in SCID mice, suggesting an important oncogenic activity of EBV in B cells. We previously showed that introduction of the BARF1 gene into the human B-cell line Louckes induced a malignant...

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Autors principals: Sheng, Wang, Decaussin, Gisèle, Ligout, Audrey, Takada, Kenzo, Ooka, Tadamasa
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149494/
https://ncbi.nlm.nih.gov/pubmed/12610162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3859-3865.2003
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