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The AKV Murine Leukemia Virus Is Restricted and Hypermutated by Mouse APOBEC3

APOBEC3 proteins are potent restriction factors against retroviral infection in primates. This restriction is accompanied by hypermutations in the retroviral genome that are attributable to the cytidine deaminase activity of the APOBEC3 proteins. Studies of nucleotide sequence diversity among endoge...

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Main Authors: Langlois, Marc-André, Kemmerich, Kristin, Rada, Cristina, Neuberger, Michael S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772689/
https://ncbi.nlm.nih.gov/pubmed/19726503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01430-09
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