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The AKV Murine Leukemia Virus Is Restricted and Hypermutated by Mouse APOBEC3

APOBEC3 proteins are potent restriction factors against retroviral infection in primates. This restriction is accompanied by hypermutations in the retroviral genome that are attributable to the cytidine deaminase activity of the APOBEC3 proteins. Studies of nucleotide sequence diversity among endoge...

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Detalhes bibliográficos
Main Authors: Langlois, Marc-André, Kemmerich, Kristin, Rada, Cristina, Neuberger, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772689/
https://ncbi.nlm.nih.gov/pubmed/19726503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01430-09
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