Human APOBEC3G Can Restrict Retroviral Infection in Avian Cells and Acts Independently of both UNG and SMUG1

APOBEC3 proteins are mammal-specific cytidine deaminases that can restrict retroviral infection. The exact mechanism of the restriction remains unresolved, but one model envisions that uracilated retroviral cDNA, generated by cytidine deamination, is the target of cellular glycosylases. While restri...

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Bibliographic Details
Main Authors: Langlois, Marc-André, Neuberger, Michael S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293047/
https://ncbi.nlm.nih.gov/pubmed/18272574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02469-07
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