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Human APOBEC3G Can Restrict Retroviral Infection in Avian Cells and Acts Independently of both UNG and SMUG1

APOBEC3 proteins are mammal-specific cytidine deaminases that can restrict retroviral infection. The exact mechanism of the restriction remains unresolved, but one model envisions that uracilated retroviral cDNA, generated by cytidine deamination, is the target of cellular glycosylases. While restri...

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書誌詳細
主要な著者: Langlois, Marc-André, Neuberger, Michael S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293047/
https://ncbi.nlm.nih.gov/pubmed/18272574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02469-07
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