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MOUSE APOBEC3 EXPRESSION IN NIH 3T3 CELLS MEDIATES HYPERMUTATION OF AKV MURINE LEUKEMIA VIRUS
Mouse APOBEC3 (mA3) is a cytidine deaminase that can act on the single-stranded DNA reverse transcripts of retroviruses resulting in G→A hypermutation of proviral DNA. Many mA3 studies have used NIH 3T3 cells assuming that endogenous mA3 production was negligible. We developed a monoclonal antibody...
Sparad:
| I publikationen: | Virology |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5918422/ https://ncbi.nlm.nih.gov/pubmed/29605684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.03.014 |
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