A carregar...
Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase η for A/T
Somatic hypermutation (SHM) introduces nucleotide substitutions into immunoglobulin variable (Ig V) region genes at all four bases, but the mutations at C/G and A/T pairs are achieved by distinct mechanisms. Mutations at C/G pairs are a direct consequence of the C→U deamination catalyzed by activati...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118430/ https://ncbi.nlm.nih.gov/pubmed/17190841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062409 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|